Indication

Peptic ulcer, Infantile colic, Upper GI bloating, Functional dyspepsia, Spastic or irritable colon

Administration

Should be taken after meals and at bedtime

Adult Dose

Adults: 40 to 125 mg (0.6 to 1.9 ml drops) 4 times daily up to 500 mg/day (7.5 ml drops). OR 1-3 chewable tablets; 4 times daily, up to 500 mg/day (12 chewable tablets).

Child Dose

Children older than 12 years of age: 40 to 80 mg (0.6 to 1.2 ml drops) 4 times daily up to 500 mg/day (7.5 ml drops). Children 2 to12 years of age: 40 mg (0.6 ml drops) 4 times daily. Children younger than 2 years of age: 20 mg (0.3 ml drops) 4 times daily up to 240 mg/day (3.6 ml drops).

Contraindication

There is no information about the contraindication of Simethicone.

Mode of Action

Changes surface tension of gas bubbles and causes collapse of foam bubbles, thus allowing easier passage of gas and preventing gas pockets in gastrointestinal tract.

Precaution

More than 12 doses per day should not be used, except under the advice and supervision of a physician. Keep the medicine out of the reach of children.

Side Effect

Simethicone is physiologically inert and no adverse effect has been reported after oral ingestion. Loose stools.