Indication

Ischaemic heart disease, Angina pectoris, Coronary heart disease

Administration

Should be taken with food.

Adult Dose

Oral Angina pectoris Adult: 40-60 mg daily in 2-3 divided doses. Modified-release tab: 35 mg bid.

Renal Dose

Renal impairment: CrCl (ml/min) Dosage Recommendation <30 Contraindicated. 30-60 20 mg bid. Modified-release: 35 mg once daily.

Contraindication

Hypersensitivity to Trimetazidine Dihydrochloride.

Mode of Action

Trimetazidine is a cellular acting anti-ischaemic agent. It has 3 main properties by which it acts as a cytoprotective agent. It inhibits the anaerobic ... View More

Precaution

Moderate renal impairment (CrCl 30-60 mL/min). Pregnancy. Patient Counselling May cause dizziness and drowsiness, if affected, do not drive or operate m... View More

Side Effect

Dizziness, headache, abdominal pain, dyspepsia, diarrhoea, nausea, vomiting, pruritus, rash, urticaria, asthenia. Rarely, tachycardia, palpitations, ext... View More

Interaction

MAOIs, nifedipine. May potentiate the effects of other antianginal